Kemi VE, Karkkainen MU, Karp HJ, Laitinen KA, Lamberg-Allardt CJ
Rates of the Beam Peat, PhD: “The fresh proportion out of calcium to help you phosphate is very important; for this reason whole milk and you will cheese are incredibly rewarding for losing weight, or for blocking putting on weight. For people who aren’t extremely energetic, zero fat whole milk and you can mozzarella cheese are better, as the extra fat fat commonly requisite.”
“The foods high in phosphate, in accordance with calcium, is actually grain, legumes, meats, and you will seafood. Of several waiting dishes consist of additional phosphate. Snacks that have a higher, safer ratio off calcium to help you phosphate is makes, eg kale, turnip veggies, and you may beet vegetables, and many fresh fruit, whole milk, and you will cheddar.”
Br J Nutr
“Free unsaturated fatty acids trigger pressure hormones, and you can cortisol stops oxidization from glucose and you may transforms they into the greasy acids and you may triglycerides. Staying cortisol and you will worry reasonable is the chief matter. Keeping a leading ratio of calcium supplements so you can phosphate helps contradict the stress k-calorie burning.” “Current guide is actually exhibiting one to way too much phosphate increases pain, tissues atrophy, calcification out-of bloodstream, malignant tumors, dementia, and you will, generally, the latest processes out of aging.”
2006 September;96(3):545-52. Higher phosphorus intakes acutely and you can negatively connect with California and you may bone k-calorie burning inside a dosage-mainly based trends inside the suit more youthful lady. Kemi VE, Karkkainen MU, Lamberg-Allardt CJ. Ca and P are each other important nourishment for bones and are generally proven to apply to probably one of the most crucial government regarding bone metabolic process, parathyroid hormone (PTH). Too substantial a great P consumption, typical out of Western dieting, will be deleterious to help you bone through the improved PTH hormonal. Couples managed dose-response research is on the effects away from highest P consumption when you look at the child. I examined the new short-label effects of four P amounts on Ca and you may bones kcalorie burning in fourteen compliment lady, 20-28 yrs old, who had been randomized in order to five regulated study weeks; therefore for every study subject supported once the her own control. P supplement amounts away from 0 (placebo), 250, 750 or 1500 milligrams had been taken, split into about three doses within the investigation date. The meals served was escort service Richardson the same throughout the per investigation day and given 495 mg P and you will 250 milligrams Ca. The newest P amounts influenced new solution PTH (S-PTH) into the a dosage-depending trends (P=0.0005). There clearly was a reduction in serum ionized Ca attention merely when you look at the the greatest P amount (P=0.004). Brand new marker from bones creation, bone-certain alkaline phosphatase, reduced (P=0.05) therefore the bone resorption marker, N-critical telopeptide out of collagen types of We, increased as a result into P amounts (P=0.05). This controlled amount-effect investigation indicated that P has actually a serving-oriented influence on S-PTH and you may increases PTH secretion notably whenever California consumption is actually lowest. Very highest P consumption adversely has an effect on bones metabolic rate of the coming down limbs formation and you will increasing limbs resorption, given that shown by limbs kcalorie burning indicators.
20 Oct 1. Increased calcium intake does not completely counteract the effects of increased phosphorus intake on bone: an acute dose-response study in healthy females. A high dietary P intake is suggested to have negative effects on bone through increased parathyroid hormone secretion, as high serum parathyroid hormone (S-PTH) concentration increases bone resorption. In many countries the P intake is 2- to 3-fold above dietary guidelines, whereas Ca intake is too low. This combination may not be optimal for bone health. In a previous controlled study, we found that dietary P dose-dependently increased S-PTH and bone resorption and decreased bone formation. The aim of the present study was to investigate the dose-response effects of Ca intake on Ca and bone metabolism with a dietary P intake higher than recommended. Each of the twelve healthy female subjects aged 21-40 years attended three 24-h study sessions, which were randomized with regard to a Ca dose of 0 (control day), 600 or 1200 mg, and each subject served as her own control. The meals on each study day provided 1850 mg P and 480 mg Ca. S-PTH concentration decreased (P < 0.001) and serum ionized Ca concentration increased (P < 0.001) with increasing Ca doses. The bone formation marker, serum bone-specific alkaline phosphatase, did not differ significantly (P = 0.4). By contrast, the bone resorption marker, urinary N-terminal telopeptide of collagen type I, decreased significantly with both Ca doses (P = 0.008). When P intake was above current recommendations, increased Ca intake was beneficial for bone, as indicated by decreased S-PTH concentration and bone resorption. However, not even a high Ca intake could affect bone formation when P intake was excessive.